ITI IMCBio+ - Integrative Molecular & Cellular Biology - University of Strasbourg https://imcbioplus.unistra.fr fr ITI IMCBio+ - Integrative Molecular & Cellular Biology - University of Strasbourg Sat, 20 Apr 2024 04:08:08 +0200 Sat, 20 Apr 2024 04:08:08 +0200 TYPO3 EXT:news news-16157 Mon, 13 May 2024 09:30:00 +0200 µNET Seminars /en/actualites/news/unet-seminars We are delighted to invite you to the µNet ZOOM-seminars on May 13th and 14th, 2024.

Dear colleagues,



We are delighted to invite you to the µNet ZOOM-seminars on May 13th and 14th, 2024.


Save the date, come listen to the 19 speakers.

It will be a unique opportunity to listen to microbiologists from all over France and get your fill of great science.


See you soon!


The µNet organizing committee.
https://sites.google.com/view/microbionetwork

]]> Actualités Agenda news-16149 Thu, 18 Apr 2024 09:00:00 +0200 What is ITI IMCBio+? Special session on biology with ITI IMCBio+ for ITI IRMIA++. /en/actualites/news/what-is-iti-imcbio-special-session-on-biology-with-iti-imcbio-for-iti-irmia The Interdisciplinary Thematic Institute IRMIA++ proposes a special session on biology, inviting ITI IMCBio+. Seminar titles

"What is the ITI IMCBio+" (Ivan Tarassov)

"Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast" (Joseph Schacherer)

"Modeling Gene Regulation Using Biophysics-Informed Deep Learning on Single-Cell Multi-Omics Data" (Nacho Molina)

More information on https://irma.math.unistra.fr/seminaires/seminaire-irmia++.html

 

 

]]> Actualités Agenda news-16140 Mon, 08 Apr 2024 14:21:44 +0200 The RNA helicase DDX5, a new regulatory protein of Sindbis virus infection /en/actualites/news/the-rna-helicase-ddx5-a-new-regulatory-protein-of-sindbis-virus-infection RNA helicases emerge as key factors regulating host-virus interactions. In this study published in “Virology Journal”, scientists have demonstrated the role of the DDX5 helicase in the replication cycle of the Sindbis virus (SINV). They were able to show that this nuclear protein is capable of relocating to the cytoplasm during SINV virus infection and directly interacting with the viral capsid, conferring a pro-viral action. RNA helicases are emerging as key regulators of viral infections. They are essential enzymes for the unfolding of RNA structures and play a crucial role in many cellular processes involving RNA, as well as in regulating various stages of viral cycles.

In this study, researchers investigated the impact of the human RNA helicase DDX5 on SINV infection, a model virus for studying other mosquito-transmitted emerging pathogens such as the Chikungunya virus. Using imaging and RNA immunoprecipitation approaches, they highlighted for the first time that DDX5 has the peculiarity of relocating from the nucleus to the cytoplasm of cells during infection by interacting with viral RNA. Furthermore, the analysis of DDX5 interactome by mass spectrometry in SINV-infected human cells identified new cellular and viral partners. The researchers identified a direct interaction between DDX5, its known cofactor DDX17, and the viral capsid. Scientists were able to demonstrate that the absence of DDX5 and its cofactor DDX17 in the cell reduces SINV infection. Conversely, overexpression of DDX5 has a positive impact on the virus, underscoring the central role played by DDX5 in host-virus interaction during the infectious cycle of SINV.

These results not only highlight that DDX5 is a novel host factor hijacked by SINV but also broaden our understanding of the roles played by DDX5 and DDX17 as regulators of viral infections. As the inhibition of both DDX5 and DDX17 reduces virus levels, further investigations are needed to better characterize these factors as potential targets for future antiviral therapies.


Messmer, M., Pierson, L., Pasquier, C. et al. DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection. Virol J. 21, 76 (2024). https://doi.org/10.1186/s12985-024-02349-3

]]> Actualités news-16050 Thu, 04 Apr 2024 08:30:00 +0200 Special scientific and technical half-day SPATIAL BIOLOGY, TRANSCRIPTOMICS, SINGLE CELL /en/actualites/news/special-scientific-and-technical-half-day-spatial-biology-transcriptomics-single-cell Special Space Biology Labcluster half-day co-organized at IBMP in partnership with IBMC and IGBMC! INVITATION

 

Scientific and technical half-day
special SPATIAL BIOLOGY, TRANSCRIPTOMICS, SINGLE CELL

 

Thursday, April 4, 2024 - 8:30am-12:30pm

Institute of Plant Molecular Biology (IBMP)
12 Rue du Général-Zimmer
67000 Strasbourg, France

             

Register

 

8h30 | Coffee and Pastries Welcome participants (salle Marie Curie)

9h00 - 9h25  | Jackson Peter, postdoc (IBMP) | Poly(A) tail length and nucleotide additions at the 3'-extremity of mRNAs detected using nanopore sequencing

9h25-9H50 | RARECYTE |Unlocking Spatial Biology with Orion™

9h50-10H15 |10X GENOMICS |Mind blowing science enabled by industry-leading single cell & spatial technologies

9h25-9H50 | STANDARD BIOTOOLS |High-plex whole slide spatial biology assays powered by the Hyperion XTi

|   Coffee Break

10h55-11h20 |  Guillaume Davidson, postdoc (IGBMC) | Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma

11h20-11h45  | NANOSTRING | Multi-Omic Spatial Profiling to Unravel Complex Biology

11h45-12h10  | LEVITAS BIO | Overcoming Sample Quality Challenges for Single Cell Analysis

12h10-12h35  | Sébastien Pfeffer, CNRS directeur de recherche, Directeur Adjoint "Architecture et Réactivité de l'ARN" (IBMC) | Noncanonical contribution of human Dicer helicase in antiviral innate immune response

•••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

12h45 - 14h00 / LUNCH offert aux participants à la matinée

•••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

STANDS OPEN ALL MORNING


Free participation upon registration.
Please note: places are limited, so register today.


Information and registration: www.labcluster.com

 

]]> Actualités Agenda news-16125 Wed, 03 Apr 2024 11:10:49 +0200 An unexpected role for the Dicer protein in the antiviral response in humans: the popularisation video! /en/actualites/news/an-unexpected-role-for-the-dicer-protein-in-the-antiviral-response-in-humans-the-popularisation-video A popular video produced by Lucie Robin, a student at the BUT "Métiers du Multimédia et de l'Internet" (Multimedia and Internet Professions) course, this video takes up this complex subject in a simple way. At the end of January 2024, a scientific mediation article concerning a publication by Sébastien Peffer's group, the "Architecture and Reactivity of arN" research unit, IBMC, Strasbourg,  was published on the CNRS Biology website: https://www.insb.cnrs.fr/fr/cnrsinfo/un-role-inattendu-pour-la-proteine-dicer-dans-la-reponse-antivirale-chez-lhomme

Aujourd’hui, nous vous proposons une vidéo de vulgarisation.

]]> Actualités news-16065 Mon, 18 Mar 2024 09:00:00 +0100 Register for the IMCBio 2024 summer school! /en/actualites/news/register-for-the-imcbio-2024-summer-school You are a second year bachelor student? You want to pursue a Master’s degree in Life Sciences? You want to discover an enthusiastic scientific environment in the heart of the Alsatian capital? So join the Summer School of the Integrative Molecular and Cellular Biology Graduate School of the University of Strasbourg!

The second edition of the IMCBio Summer School will take place between June 25 and June 28 in Strasbourg*!

  • Experience Sci-fun
  • Meet biology experts
  • Visit top research facilities
  • Assist to scientific lectures
  • Participate to social events
  • Discover the Alsatian charm
  • And have the opportunity of getting 1-month financially supported internship!**

You can apply here until May 17, places are limited so don’t miss your chance!

*Travel fees & accommodation provided; in-city transport, food & internship fellowships, all available after application review

**Within the limits of available fellowships

]]> Actualités Agenda news-16013 Fri, 23 Feb 2024 10:33:31 +0100 Junior chair position - BIOLOGY OF HOST-PATHOGEN INTERACTIONS BEYOND VERTEBRATES /en/actualites/news/junior-chair-position-biology-of-host-pathogen-interactions-beyond-vertebrates The CNRS research department “Insects Models of Innate Immunity” invites applications for a group leader position. Junior chair position

BIOLOGY OF HOST-PATHOGEN INTERACTIONS BEYOND VERTEBRATES

CNRS Strasbourg (France)

 

The CNRS research department “Insects Models of Innate Immunity” invites applications for a group leader position. Applicants must have a strong record of scientific accomplishments in innate immunity or host-pathogen interactions, preferentially in non-mammalian models. We are looking for candidates who will bring new lines of research to the department (evolution, regulation of gene expression, metabolism, bioinformatics, etc…) and willing to work collaboratively with existing groups in the NetRNA LabEx network (https://labex-netrna.cnrs.fr/presentation/netrna-teams/).

The department “Insects Models of Innate Immunity” performs cutting edge basic research on insect-pathogen interactions, focusing on the fruit-fly Drosophila as well as vector mosquitoes Anopheles and Aedes (https://ibmc.cnrs.fr/en/laboratoire/m3i/). It is located in the Institute of Molecular and Cellular Biology (IBMC) on the central campus of the University of Strasbourg, France. IBMC offers an excellent research environment, with state-of-the-art facilities and infrastructure for proteomics, genomics, cell imaging and an insectarium dedicated to studies in infectiology with BSL3 containment. Our department participates in the NetRNA consortium, which offers an attractive start-up package that includes salary and research support for 3-5 years.

Applicants should submit a curriculum vitae, a summary of research accomplishments (1-2 pages), a summary of future research plans (1-2 pages) and contact information for three professional references. Applications in the form of a single pdf document, or any question regarding the position, should be sent to bstevenin[at]unistra.fr.

 

]]> Actualités news-15868 Tue, 13 Feb 2024 14:00:00 +0100 P3N Workshop /en/actualites/news/p3n-workshop Le réseau P3N propose 2 séminaires sur la purification des protéines ! Actualités Agenda news-15844 Wed, 06 Dec 2023 13:28:45 +0100 2024 IMCBio international PhD Call is now! /en/actualites/news/2024-imcbio-international-phd-call-is-now The 2024 IMCBio international PhD Call will be launched on January 8, 2024. Project submission is possible until January 8, 2024. Given external administrative constraints, a single call will take place again this year.  As in previous IMCBio PhD Calls, you have different types of project that you can submit to host a student in your team in 2024:

  • You can propose a single team project (supported by Cluster Research (/LabEx) funding). As a reminder, each Cluster Research has to organise its internal scientific priorities (eligibility, number of fellowships...) within the common Graduate School guidelines.

  • You can submit a collaboration project involving two teams from two different IMCBio Cluster Research (INRT, NetRNA, MitoCross, HepSYS). Up to two doctoral contracts will be supported by the IMCBio Graduate School funds in 2024. Important: note that this year again, to allow applicants to get a better grasp of these collaboration projects and identify a main contact, one of the host team will be presented as the main project coordinator as the second team as the collaborator. The project needs to rely on strong collaboration to warrant support by the IMCBio Graduate School.

  • You can submit a project with your own-funding (whatever the source of funding already acquired). 

And this year we propose you a new possibility: 

  • You can submit a team-platform collaboration project involving, a research team and a technology platform if possible from two different IMCBio Cluster Research (INRT, NetRNA, MitoCross, HepSYS, note that this is not an absolute criteria). Up to three doctoral contracts will be supported by the IMCBio Graduate School funds in 2024. These projects will have for objective the development of a new method (not incremental progress or implementation of existing processes) that have the potential to result in a methodological leap forward associated to technology transfer (in this vein a link with a private company could be a plus). Note that this action is intended primarily to support to develop new technologies and not an alternative to support existing team projects. Importantly, for these new type of projects, a validation step by the IMCBio executive committee will occur before posting of selected projects the IMCBio PhD Call web site. The PhD student supervision has to be assumed by an HDR identified as the main contact (team or platform) with the second partner identified as the collaborator.

As a reminder: each Cluster Research (/LabEx) has to organize its internal scientific priorities for LabEx funded grants following the common Graduate School guidelines. If you are interested by submitting a collaboration project (team-team or team-platform; IMCBio Graduate School funded grants), please inform first your LabEx director before sending the collaboration project to me.

For each selected project, I will need the corresponding form attached dully filled. 

Please, note that you are also welcome to advertise a project on your own funds. If you are interested, you can send me directly the attached form.

 

For all questions, please contact :

Gwenaëlle Graulier, PhD

https://imcbio.unistra.fr

As in previous IMCBio PhD Calls, you have different types of project that you can submit to host a student in your team in 2024:

  • You can propose a single team project (supported by Cluster Research (/LabEx) funding). As a reminder, each Cluster Research has to organise its internal scientific priorities (eligibility, number of fellowships...) within the common Graduate School guidelines.

  • You can submit a collaboration project involving two teams from two different IMCBio Cluster Research (INRT, NetRNA, MitoCross, HepSYS). Up to two doctoral contracts will be supported by the IMCBio Graduate School funds in 2024. Important: note that this year again, to allow applicants to get a better grasp of these collaboration projects and identify a main contact, one of the host team will be presented as the main project coordinator as the second team as the collaborator. The project needs to rely on strong collaboration to warrant support by the IMCBio Graduate School.

  • You can submit a project with your own-funding (whatever the source of funding already acquired). 

And this year we propose you a new possibility: 

  • You can submit a team-platform collaboration project involving, a research team and a technology platform if possible from two different IMCBio Cluster Research (INRT, NetRNA, MitoCross, HepSYS, note that this is not an absolute criteria). Up to three doctoral contracts will be supported by the IMCBio Graduate School funds in 2024. These projects will have for objective the development of a new method (not incremental progress or implementation of existing processes) that have the potential to result in a methodological leap forward associated to technology transfer (in this vein a link with a private company could be a plus). Note that this action is intended primarily to support to develop new technologies and not an alternative to support existing team projects. Importantly, for these new type of projects, a validation step by the IMCBio executive committee will occur before posting of selected projects the IMCBio PhD Call web site. The PhD student supervision has to be assumed by an HDR identified as the main contact (team or platform) with the second partner identified as the collaborator.

As a reminder: each Cluster Research (/LabEx) has to organize its internal scientific priorities for LabEx funded grants following the common Graduate School guidelines. If you are interested by submitting a collaboration project (team-team or team-platform; IMCBio Graduate School funded grants), please inform first your LabEx director before sending the collaboration project to me.

For each selected project, I will need the corresponding form attached dully filled. 

Please, note that you are also welcome to advertise a project on your own funds. If you are interested, you can send me directly the attached form.

 

For all questions, please contact :

Gwenaëlle Graulier, PhD

Monday, Wednesday & Thursday :
IGBMC – office 1016
1 rue Laurent Fries
67400 Illkirch-Graffenstaden
+33 (0)3.88.65.33.03

Tuesday & Friday :
GMGM – 3rd floor
21 rue René Descartes
67000 Strasbourg
+33 (0)3.68.85.14.60

]]> Actualités news-15841 Wed, 06 Dec 2023 11:57:50 +0100 Thomas Baumert wins the INSERM 2023 prize /en/actualites/news/thomas-baumert-wins-the-inserm-2023-prize Thomas Baumert has just been awarded the INSERM 2023 prize for his work in furthering knowledge of fibrosis and liver cancer. We congratulate Thomas BAUMERT, labEx Hepsys, on winning this prize.

A short video presentation of the researcher's work

]]> Actualités news-15833 Mon, 04 Dec 2023 08:25:27 +0100 They're talking about us at... "2022 une année avec le CNRS en Alsace" /en/actualites/news/theyre-talking-about-us-at-2022-une-annee-avec-le-cnrs-en-alsace "CoLoC-seq, pour bien localiser les ARN dans la cellule", "SFPQ, protéine détournée par le virus SINV... CQFD !" or even innovation avec FUNAMBULIST, find out more about our teams / research through various articles from "2022 une année avec le CNRS en Alsace" ! Recherche

Retrouvez p.20

CoLoC-seq, pour bien localiser les ARN dans la cellule

Au sein d’une cellule, on trouve différents composants, ou organites, individualisés par une membrane (noyau, mitochondrie, appareil de Golgi, …). Pour chaque organite, les généticiens ont besoin de déterminer la localisation précise des ARN produits à partir de l’ADN. En effet, leur localisation correcte est nécessaire à l’expression des gènes. Problème, les techniques utilisées, quand elles reposent sur l’utilisation d’enzymes de type RNases, confondent souvent les ARN de l’organite étudié, dits « résidents », des ARN produits ailleurs, dits « contaminants ». Pour les distinguer, les chercheurs proposent CoLoC-seq, nouvelle méthode qui repose sur la cinétique enzymatique et une modélisation mathématique.
Nucleic Acids Research | décembre 2022
Génétique moléculaire, génomique, microbiologie

Retrouvez p.38

SFPQ, protéine détournée par le virus SINV... CQFD !

Les virus sont des parasites obligatoires, qui dépendent de la cellule qu’ils infectent pour multiplier leur génome et se propager. Lors de la réplication, les virus à ARN produisent un ARN double brin (ARNdb), qui est perçu par la cellule comme signal de danger et va déclencher la réponse antivirale. Les virus ont mis au point diverses stratégies pour contourner cette réponse. Il est par conséquent crucial d’identifier les protéines cellulaires que le virus détourne dans ce but. Les scientifiques ont conduit leur étude sur le virus de Sindbis. Parmi les protéines reconnaissant l’ARNdb viral, ils ont pu identifier la protéine SFPQ (splicing factor, proline-glutamine rich) comme facteur pro-viral.
RNA | décembre 2022
Architecture et réactivité de l'ARN

Mais aussi en médiation

Retrouvez p.32

Finale Alsace MT180

Trois minutes pour présenter sur scène ses travaux de thèse, sans autre accessoire qu’un unique visuel ! C’est le défi lancé aux doctorant(e)s du concours Ma thèse en 180 secondes, co- organisé par le Jardin des sciences de l’Université de Strasbourg et la délégation Alsace du CNRS. Trois prix ont été décernés au cours de la 9e édition régionale. Ils ont été remportés par Anne Cousin (Institut de biologie moléculaire des plantes | IBMP), lauréate du 1er prix du jury et du prix du public, et par Alexandra Helleux (Institut de génétique et de biologie moléculaire et cellulaire | IGBMC), 2 e prix du jury.

Ou encore en innovation

Retrouvez p.35

Conseil européen de l’innovation

Lancé avec le programme Horizon Europe en 2021, l’EIC vise à accompagner les innovations de rupture, de leur émergence à leur mise sur le marché. Le dispositif « Pathfinder » s’intéresse aux projets de recherche portant sur les premiers développements d’une technologique innovante. Ce dispositif permet en outre d'obtenir des moyens pour avancer et établir une preuve de concept.
FUNAMBULIST vise une production radicalement nouvelle de produits chimiques, grâce à des processus catalytiques basés sur des acides nucléiques (ADN ou ARN) dans des solvants non conventionnels, tels que des liquides ioniques.
Institut de science et d'ingénierie supramoléculaires
Architecture et réactivité de l'ARN

]]> Actualités news-15792 Wed, 22 Nov 2023 09:13:40 +0100 Welcome to Prof Georg STOECKLIN at IMCBio+ ITI /en/actualites/news/welcome-to-prof-georg-stoecklin-at-imcbio-iti Prof Georg STOECKLIN, who has just joined the IGBMC/EIR IMCBio/ITI IMCBio+ on sabbatical. Georg Stoecklin is professor for biochemistry at Heidelberg University, Germany. He earned an MD and PhD in Biology at the University of Basel, Switzerland. Following postdoctoral training at the Brigham and Women’s Hospital / Harvard Medical School in Boston, USA, he became junior group leader at the German Cancer Research Center in Heidelberg. Since 2016, he heads the Division of Biochemistry at the Medical Faculty Mannheim of Heidelberg University. He is also director of the Faculty Core Technology Platform and co-director of the Mannheim Institute of Innate Immunoscience. Pr Georg Stoecklin joined the IGBMC / Illkirch for a sabbatical and is hosted by Bertrand Séraphin. During his time in Strasbourg, he is Associated Chair of RNA Biology at the USIAS / University of Strasbourg. He will give a first conference "Insights into the control of mammalian mRNA splicing, translation and decay" at the IBMC on 08/12/2023 at 11am.

]]> Actualités news-15771 Mon, 20 Nov 2023 10:21:37 +0100 The IMCBio 2023 school symposium is now open! /en/actualites/news/the-imcbio-2023-school-symposium-is-now-open High-level lectures in the fields of biology for the school's Master 2 students. 20 speakers from France, Germany, Japan, Norway, Scotland, Spain, Switzerland and USA. The subjects covered: Plant biology, Virology, Immunology, Genetics and Molecular Biology as well as Structural and Developmental Biology.

As in previous years, the Immunology Symposium with the University of Strasbourg's Faculty of Life Sciences was co-organised at the same time.

More information on the IMCBio School website

 

 

]]> Actualités news-15763 Wed, 15 Nov 2023 09:59:22 +0100 Portrait of the new manager at IMCBio /en/actualites/news/portrait-of-the-new-manager-at-imcbio Welcome to Gwenaëlle Graulier! "A microbiologist by training, I began my career as a research engineer in the Biotechnology and Cell Signalling Laboratory after studying at the University of Strasbourg (IUT Louis Pasteur and then the Faculty of Life Sciences). I then decided to try my hand at the great adventure of a PhD in the same laboratory, working on a pathogenic bacterium, its infection in people with cystic fibrosis and its relationship with iron. Following this, and charmed by teaching, I was given the opportunity to teach a Biology Engineering degree at the IUT Louis Pasteur, where I taught various subjects related in one way or another to molecular biology. I've now moved on to another facet of university education as head of EUR IMCBio."

]]> Actualités news-15761 Wed, 15 Nov 2023 08:12:27 +0100 From laboratory to business /en/actualites/news/from-laboratory-to-business Start-up incubator BaseLaunch, which focuses on supporting start-ups in the field of therapeutics, is holding an event in Strasbourg on 28 November. For this event, high-level speakers will give presentations and answer questions on the success of biotech companies. The event is free of charge and the focus is on providing information to start-up companies or university researchers thinking about entrepreneurship. More information can be found in the document below or on the event webpage.

]]> Actualités news-15601 Tue, 12 Sep 2023 09:30:20 +0200 Prix Espoirs 2023: six researchers honoured /en/actualites/news/prix-espoirs-2023-six-researchers-honoured This year, six researchers, including Eloi Verrier - Hepsys Research Cluster, were awarded the scientific prize "Les Espoirs de l'Université de Strasbourg". The awards were presented at the new academic year ceremony held on Thursday in the Patio's Cavaillès amphitheatre. Let's congratulate Eloi Verrier, Institut de recherche sur les maladies virales et hépatiques (IVH - Inserm/Unistra), for this fine reward!

Savoir(s) | Le quotidien de l'Université de Strasbourg

]]> Actualités news-15454 Mon, 10 Jul 2023 09:24:44 +0200 MCOPS12: joint treatment development with an international association /en/actualites/news/mcops12-joint-treatment-development-with-an-international-association Syndromic microphthalmia 12 (MCOPS12) is a rare genetic disease causing microphthalmia, as well as significant motor and intellectual disorders. In collaboration with Canadian, Swiss and French scientists, supported by funds from the European Community and the Cure MCOPS12 association, Wojciech Krezel's group is studying the mechanisms of neurodegeneration in this disease, with a the aim of developing a therapeutic strategy.

See the article on the INRT website

]]> Actualités news-15460 Fri, 30 Jun 2023 13:17:00 +0200 IMCBio Summer School /en/actualites/news/imcbio-summer-school The IMCBio summer school was held from June 28 to 30, 2023! Undergraduates from all over the world, from France and Greece, came together for this summer school.

The program included lectures, experiments, visits and convivial moments to discover our fabulous research and the teaching offered at this school.

]]> Actualités news-15456 Thu, 29 Jun 2023 09:27:00 +0200 Nervspan: a Europe-wide research training network /en/actualites/news/nervspan-a-europe-wide-research-training-network Announced in spring 2023, the European Nervspan network will bring together a dozen laboratories and industrial partners to train doctoral students. Bringing together teams with expertise in the neural development of the C. elegans model, this network offers students the opportunity to be trained in research within a multi-disciplinary framework on a European scale. It enables students to gain initial experience of international research collaboration and to develop their career plans. Registrations are open until July 14.

See the article on the INRT website

]]> Actualités news-15452 Wed, 28 Jun 2023 09:18:00 +0200 Muscle aging: a collaboration to understand the impact of the endoplasmic reticulum /en/actualites/news/muscle-aging-a-collaboration-to-understand-the-impact-of-the-endoplasmic-reticulum The endoplasmic reticulum is a cellular structure responsible for protein synthesis and trafficking. This structure is maintained by a recycling process that eliminates damaged or useless parts. However, it tends to become dysregulated in muscle cells with advancing age. To better understand the consequences in muscle aging, Minchul Kim and Marcus Rüegg, researcher at the Biozentrum of the University of Basel, have launched a joint research project.

See the article on the INRT website

]]> Actualités news-15311 Wed, 28 Jun 2023 09:00:00 +0200 IMCBio Summer School /en/actualites/news/ecole-dete-imcbio-1 The first edition of the IMCBio Summer School will take place this year from June 28-30, 2023. The aim of this Summer School is to get talented Bachelor students in their 2nd year to know the IMCBio program and the associated labs, as well as the city of Strasbourg, to motivate them to join IMCBio for their Masters and PhD. With support from IMCBio, we plan to host 20 students registered in European universities (external to Strasbourg) and up to 20 local students from Strasbourg. During their stay, students will have the opportunity to visit and listen to presentations from the different IMCBio components and partners with the following tentative program:

Day 1 - Esplanade/IBMC-IBMP-GMGM

Day 2 - Illkirch/IGBMC

Day 3 - Hospital/HepSYS/Life Science Faculty
This first event is being organized with the help of a team of 10 PhD students*, they might contact you or people in your team to participate to presentations.

Please, note that some of the non-Strasbourg students may also be selected from a one month internship in a IMCBio lab.

The website of the Summer School, with the preliminary schedule and application forms are now online: https://imcbio.unistra.fr/imcbio-training-programs/summer-school/

]]> Agenda news-15411 Thu, 22 Jun 2023 10:54:48 +0200 2023 μNET Strasbourg meeting /en/actualites/news/2023-mnet-strasbourg-meeting On June 23, 2023, a one-day seminar will be held with Dr. Thomas Kehl-Fie (University of Illinois at Urbana-Champaign, USA) in the IBMC seminar room. The main objective of his research is to understand how the opportunistic pathogen Staphylococcus aureus obtains and copes with the absence of essential inorganic nutrients, such as metals, during infection.

This plenary lecture will be followed by short presentations by members of µNET Strasbourg, a network of recently recruited researchers in Microbiology. This network, still in its infancy, was born in Marseille and has since been emulated in several major cities, including Strasbourg, Lyon and Toulouse. The idea of the network is to help new microbiologists get their bearings, support each other at the start of their careers, encourage scientific and practical exchanges and facilitate the integration of new researchers into the Strasbourg and national landscape.

Please confirm your attendance by following the link below:  https://evento.renater.fr/survey/participation-to-net...-ggsfdtpe


We hope to see many of you,
David Lalaouna and Pascale Romby

]]> Actualités news-15409 Thu, 22 Jun 2023 10:33:47 +0200 New jobs at Hepsys /en/actualites/news/new-jobs-at-hepsys The HepSYS LabEx has two new vacancies: - MD/PhD position in Translational Medicine for Liver Diseases: open to doctors only. - Project Manager position

Go to the LabEx Hepsys website

]]> Actualités news-15446 Mon, 19 Jun 2023 15:47:00 +0200 Three IGBMC doctoral students win prizes from the Strasbourg Biology Society /en/actualites/news/three-igbmc-doctoral-students-win-prizes-from-the-strasbourg-biology-society This year, three IGBMC doctoral students received a thesis prize from the Société de biologie de Strasbourg. Well done to Manon Boivin, Yuri Zgadzay & Théo Aspert!

For more information, see the article on the INRT website

]]> Actualités news-15450 Sat, 17 Jun 2023 16:12:00 +0200 Johann Böhm, winner of the Rhineland Academy Prize /en/actualites/news/johann-boehm-winner-of-the-rhineland-academy-prize INRT member Johann Böhm has been awarded the Rhineland Academy Science Prize, the organisation announced on 17 June. Mettant en valeur l’excellence alsacienne, ce prix vient récompenser la contribution du scientifique à la compréhension des myopathies à agrégats tubulaires. Pour lutter contre cette maladie génétique, Johann Böhm a notamment participé à l’identification de ses bases génétiques, à la compréhension de son développement et à l’élaboration de preuves de concepts thérapeutiques. Ces dernières ont donné lieu à la publication d’un brevet. Précédemment, d’autres scientifiques IGBMC ont été lauréats dans cette catégorie : Agnès Bloch-Zupan, en 2017 et Hélène Puccio, en 2014.

Pour en savoir plus sur les recherches de Johann Böhm, click here.

]]> Actualités news-15203 Fri, 16 Jun 2023 08:30:00 +0200 IGBMC Partnership Day /en/actualites/news/igbmc-partnership-day Is your field of activity biology research, pharmaceutical research, health, biotechnology? On Friday 16 June, the IGBMC invites you to a day of meetings and presentation of its technological resources on its premises.

Free registration is required

]]> Actualités Agenda news-15448 Wed, 14 Jun 2023 16:04:00 +0200 Fondation Force Prize: Agnès Bloch-Zupan winner /en/actualites/news/fondation-force-prize-agnes-bloch-zupan-winner Agnès Bloch-Zupan and her team have won a prize from the Force Foundation, the organisation announced on 13 June. This prize is in support of their D_ia_gno_dent project, which aims to develop a virtual assistant to reduce diagnostic error among patients suffering from a rare oral disease.

For more information about the Force Foundation, click here.

]]> Actualités news-15366 Fri, 26 May 2023 09:53:05 +0200 Androgen receptor coordinates metabolic and contractile functions of skeletal muscle /en/actualites/news/androgen-receptor-coordinates-metabolic-and-contractile-functions-of-skeletal-muscle Androgens are steroid hormones that affect muscle structure and strength whose action is mediated by the androgen receptor. In a study published in the Journal of Cachexia Sarcopenia and Muscle, the research group coordinated by Dr. Daniel Metzger and Dr. Delphine Duteil, INRT cluster, characterized the effect of the absence of the androgen receptor in skeletal striated muscle fibers, leading to the development of muscle weakness and type 2 diabetes, and identified the underlying molecular mechanisms.

More informations on INRT Website

]]> Actualités news-15094 Tue, 23 May 2023 09:00:00 +0200 Symposium StraARS 2023 /en/actualites/news/symposium-straars-2023 StraARS 2023 – "Aminoacyl-tRNA synthetases : sculpting codes and shaping cell physiology" is a international meeting which will focus on three fundamental facets of the research on tRNA and aminoacyl-tRNA synthetases. The web site for more informations and subscription is https://straars2023.org.

]]> Actualités Agenda news-15327 Fri, 12 May 2023 08:50:49 +0200 Four young scientists from the IMCBio+ IIT awarded during the Doctoral School Days 2023 /en/actualites/news/four-young-scientists-from-the-imcbio-iit-awarded-during-the-doctoral-school-days-2023 During the Doctoral School Days 2023, prizes were awarded to doctoral students for the quality of their presentations and posters. Four young scientists from the IGBMC, INRT research cluster, ITI IMCBio+, were awarded for their work.

More informations

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